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Noreen Morris

Lecturer/Researcher Organic Chemistry

  • nmorris@ait.ie
  • Room: E63
  • Building: Main Campus
  • Faculty: Faculty of Science and Health

Ph.D.

Synthetic Organic Chemistry, National
University of Ireland-NUI Galway 1989

B.Sc. (Hons.) Chemistry, National University of Ireland-NUI Galway
1984

Research

interests:

• synthesis and separation of chiral intermediates using enzymatic
techniques,

• organometallic chemistry,

• polymer chemistry,

• pharmaceutical synthesis,

• spectroscopic analysis, Research Experience

• pharmaceutical materials/hydrogels,

• development of analytical techniques in sports science and
synthesis

• characterisation of new psychoactive substances (NPS)Research
Experience

Current Research:

I’m working closely with the fine
chemical industry in the area of biocatalysis in an effort to displace
multistep chemical routes for the synthesis of pharmaceuticals with lower cost
and less polluting enzymatic processes. . This research will contribute to
both synthetic and analytical chemistry on a national and international
basis, and strengthen collaborative links with other research active
institutions and practitioners.

Orcid ID:
0000-0001-5892-1441

Publications:

1. Noreen Morris Niall Geraghty, Synthesis of 2-Alkyl Cyclopen-2-en-1-ones. A versatile kinetic alkylation-ozonolysis
procedure for the preparation of -ketoaldehydes. Synthesis Journal of Synthetic Organic
Chemistry, 603-607, 1989.

2. Noreen Morris, Brian Greally, Peter Cairns, An investigation of factors
influencing the resolution of chiral alkyl aromatic amines on a
dinitrobenzoyl - (S) - leucine column.
Journal of Liquid Chromatography and Related Technologies, 19(3), 489
- 502, 1996

.

3. Noreen Morris, Andrzej Stanczuk, Elizabeth Gardner, Pierce Kavanagh.
Identification of (2-aminopropyl) benzofuran (APB) phenyl ring positional
isomers in internet products. Drug testing and analysis. 5 270-276 ,
2013

4. Noreen Morris, Gavin McLaughlin, Michael H. Baumann, Pierce V. Kavanagh,
John D. Power, Geraldine Dowling, Brendan Twamley, John O’Brien, Gary
Hessman, Folker Westphal, Donna Walther, Simon D. Brandt. Synthesis,
analytical characterisation and monoamine transporter activity of the new
psychoactive substance 4-methylphenmetrazine (4-MPM), with differentiation
from its ortho- and meta- positional isomers. Drug Testing and Analysis.
2018, 10, 1404-1416. DOI: 10.1002/dta.2396.

5. Noreen Morris, Gavin McLaughlin, Pierce V. Kavanagh, John D. Power,
Geraldine Dowling, Brendan Twamley, John O’Brien, Gary Hessman, Brian Murphy,
Donna Walther, John S. Partilla, Michael H. Baumann, Simon D. Brandt.
Analytical characterization and pharmacological evaluation of the new
psychoactive substance 4-fluoromethylphenidate (4F-MPH) and differentiation
between the ()-threo and ()-erythro diastereomers. Drug Testing and
Analysis. 2017, 9, 347-357. DOI: 10.1002/dta.2167

6. Noreen Morris, Gavin McLaughlin, Pierce V. Kavanagh, John D. Power,
Geraldine Dowling, Brendan Twamley, John O’Brien, Brian Talbot, Donna Walther,
John S. Partilla, Michael H. Baumann, Simon D. Brandt. Synthesis,
characterization and monoamine transporter activity of the new psychoactive
substance mexedrone and its N-methoxy positional isomer, N-methoxymephedrone.
Drug Testing of their thermal stability. Drug Testing and Analysis. 2017, 9,
311-316. DOI: 10.1002/dta.1950.

7. Noreen Morris, Gavin McLaughlin, Pierce V. Kavanagh, Geraldine Dowling,
John D. Power, Brendan Twamley, John O’Brien, Brian Talbot, Harald H. Sitte,
Simon D. Brandt. Test purchase, synthesis and characterization of
3-fluorophenmetrazine (3-FPM) and differentiation from its ortho- and
para-substituted isomers. Drug Testing and Analysis. 2017, 9, 369-377. DOI:
10.1002/dta.1945.

8. Noreen Morris, Gavin McLaughlin, Pierce V. Kavanagh, John D. Power,
Brendan Twamley, John O’Brien, Brian Talbot, Geraldine Dowling, Simon D.
Brandt. The synthesis and characterisation of the ‘research chemical’
N-(1-amino-3-methyl-1-oxobutan-2-yl)-1-(cyclohexylmethyl)-3-(4-fluorophenyl)-1H-pyrazole-5-carboxamide
(3,5-AB-CHMFUPPYCA) and differentiation from its 5,3-regioisomer. Drug
Testing and Analysis. 2016, 8, 920-929. DOI: 10.1002/dta.1864.

9. Noreen Morris, Gavin McLaughlin, Pierce V. Kavanagh, John D. Power, John
O’Brien, Brian Talbot, Simon P. Elliott, Jason Wallach, K. Hoang, Hamilton
Morris, Simon D. Brandt. Test purchase, synthesis and characterization of
2-methoxydiphenidine (MXP) and differentiation from its meta- and
para-substituted isomers. Drug Testing and Analysis. 2015, 8, 98-109. DOI:
10.1002/dta.1800.

10. Noreen Morris, Gavin McLaughlin, Pierce V. Kavanagh, John D. Power,
Brendan Twamley, John O’Brien, Brian Talbot, Geraldine Dowling, Olivia
Mahony, Simon D. Brandt, Julian Patrick, Roland P. Archer, John S. Partilla,
Michael H. Baumann. Synthesis, characterization and monoamine transporter
activity of the new psychoactive substance
3’,4’-methylenedioxy-4-methylaminorex (MDMAR). Drug Testing and Analysis.
2014, 7, 555-564. DOI: 10.1002/dta.1732.

11. Noreen Morris, Jason Wallach,
Pierce V. Kavanagh, Gavin McLaughlin, John D. Power, Simon P. Elliott, Marion
S. Mercier, David Lodge, Hamilton Morris, Nicola M. Dempster, Simon D.
Brandt. Preparation and characterization of the ‘research chemical’
diphenidine, its pyrrolidine analogue, and their 2,2-diphenylethyl isomers.
Drug Testing and Analysis. 2014, 7, 358-367. DOI: 10.1002/dta.1689

.

12. Noreen Morris, Fashli Razak, Vlasta Chyzna, Alan Murphy, James Kennedy.
An investigation into the effects of pH and material concentrations on the
morphology of Chitosan-Alginate microspheres prepared using an Ionic Gelation
techniques”. International Journal
of Advance Scientific Research and Management, Vol. 2 Issue 10, October 2017.

13. Noreen Morris, Fashli Razak, James Kennedy, Alan Murphy. Development of
Amoxicillin loaded microspheres for anti-Helicobacter pylori infection using
Ionic Gelation Method. International Journal of Advance Scientific Research
and Management, November 2017

14. Noreen Morris, Maya Hotta, James Kennedy, Clem Higginbotham. Durum
wheat seed germination response to hydrogel coatings and moisture under
drought stress, American Journal of Agricultural and Biological Sciences, 11
(2), 67-75 (2016).

15. Noreen Morris, Maya Hotta, James Kennedy, Clem. Higginbotham.
Development of seed coating agent with ι-carrageenan hydrogel for
sustainable agriculture, Journal of the Institute of Chemistry of Ireland,
July (3), 36-37 (2016).

16. Noreen Morris, Maya Hotta, James Kennedy, Clem Higginbotham,
“ι-Carrageenan hydrogel seed coating for drought mitigation &
sustainable agriculture”, Environews (2017).

17. Noreen Morris, Maya Hotta, James Kennedy, Clem Higginbotham. Synthesis
and characterisation of novel ι-carrageenan hydrogel blends for agricultural
seed coating application, Applied Mechanics and Materials, 679, 81-91
(2014).

Lecturing

Experience: I lecture on undergraduate courses in the following
modules:

• Organic Chemistry;

• Synthetic Organic Chemistry;

• Pharmaceutical Materials;

• Pharmaceutical Spectroscopy;

• Pharmaceutical Synthesis;

• Analytical techniques;

• Contemporary issues in pharmaceutical science;

• Medical devices and advanced therapies.

"Scifest Co-ordinator: AIT Scifest co-ordinator providing an opportunity for second level students in the midlands to showcase their skills in Science Technology Engineering and Maths and at the same time to develop their critical thinking and problem solv

MICI, MRSC. CChem


  • Biography

    Ph.D.

    Synthetic Organic Chemistry, National
    University of Ireland-NUI Galway 1989

    B.Sc. (Hons.) Chemistry, National University of Ireland-NUI Galway
    1984

  • Research & Consultancy

    Research

    interests:

    • synthesis and separation of chiral intermediates using enzymatic
    techniques,

    • organometallic chemistry,

    • polymer chemistry,

    • pharmaceutical synthesis,

    • spectroscopic analysis, Research Experience

    • pharmaceutical materials/hydrogels,

    • development of analytical techniques in sports science and
    synthesis

    • characterisation of new psychoactive substances (NPS)Research
    Experience

    Current Research:

    I’m working closely with the fine
    chemical industry in the area of biocatalysis in an effort to displace
    multistep chemical routes for the synthesis of pharmaceuticals with lower cost
    and less polluting enzymatic processes. . This research will contribute to
    both synthetic and analytical chemistry on a national and international
    basis, and strengthen collaborative links with other research active
    institutions and practitioners.

    Orcid ID:
    0000-0001-5892-1441

    Publications:

    1. Noreen Morris Niall Geraghty, Synthesis of 2-Alkyl Cyclopen-2-en-1-ones. A versatile kinetic alkylation-ozonolysis
    procedure for the preparation of -ketoaldehydes. Synthesis Journal of Synthetic Organic
    Chemistry, 603-607, 1989.

    2. Noreen Morris, Brian Greally, Peter Cairns, An investigation of factors
    influencing the resolution of chiral alkyl aromatic amines on a
    dinitrobenzoyl - (S) - leucine column.
    Journal of Liquid Chromatography and Related Technologies, 19(3), 489
    - 502, 1996

    .

    3. Noreen Morris, Andrzej Stanczuk, Elizabeth Gardner, Pierce Kavanagh.
    Identification of (2-aminopropyl) benzofuran (APB) phenyl ring positional
    isomers in internet products. Drug testing and analysis. 5 270-276 ,
    2013

    4. Noreen Morris, Gavin McLaughlin, Michael H. Baumann, Pierce V. Kavanagh,
    John D. Power, Geraldine Dowling, Brendan Twamley, John O’Brien, Gary
    Hessman, Folker Westphal, Donna Walther, Simon D. Brandt. Synthesis,
    analytical characterisation and monoamine transporter activity of the new
    psychoactive substance 4-methylphenmetrazine (4-MPM), with differentiation
    from its ortho- and meta- positional isomers. Drug Testing and Analysis.
    2018, 10, 1404-1416. DOI: 10.1002/dta.2396.

    5. Noreen Morris, Gavin McLaughlin, Pierce V. Kavanagh, John D. Power,
    Geraldine Dowling, Brendan Twamley, John O’Brien, Gary Hessman, Brian Murphy,
    Donna Walther, John S. Partilla, Michael H. Baumann, Simon D. Brandt.
    Analytical characterization and pharmacological evaluation of the new
    psychoactive substance 4-fluoromethylphenidate (4F-MPH) and differentiation
    between the ()-threo and ()-erythro diastereomers. Drug Testing and
    Analysis. 2017, 9, 347-357. DOI: 10.1002/dta.2167

    6. Noreen Morris, Gavin McLaughlin, Pierce V. Kavanagh, John D. Power,
    Geraldine Dowling, Brendan Twamley, John O’Brien, Brian Talbot, Donna Walther,
    John S. Partilla, Michael H. Baumann, Simon D. Brandt. Synthesis,
    characterization and monoamine transporter activity of the new psychoactive
    substance mexedrone and its N-methoxy positional isomer, N-methoxymephedrone.
    Drug Testing of their thermal stability. Drug Testing and Analysis. 2017, 9,
    311-316. DOI: 10.1002/dta.1950.

    7. Noreen Morris, Gavin McLaughlin, Pierce V. Kavanagh, Geraldine Dowling,
    John D. Power, Brendan Twamley, John O’Brien, Brian Talbot, Harald H. Sitte,
    Simon D. Brandt. Test purchase, synthesis and characterization of
    3-fluorophenmetrazine (3-FPM) and differentiation from its ortho- and
    para-substituted isomers. Drug Testing and Analysis. 2017, 9, 369-377. DOI:
    10.1002/dta.1945.

    8. Noreen Morris, Gavin McLaughlin, Pierce V. Kavanagh, John D. Power,
    Brendan Twamley, John O’Brien, Brian Talbot, Geraldine Dowling, Simon D.
    Brandt. The synthesis and characterisation of the ‘research chemical’
    N-(1-amino-3-methyl-1-oxobutan-2-yl)-1-(cyclohexylmethyl)-3-(4-fluorophenyl)-1H-pyrazole-5-carboxamide
    (3,5-AB-CHMFUPPYCA) and differentiation from its 5,3-regioisomer. Drug
    Testing and Analysis. 2016, 8, 920-929. DOI: 10.1002/dta.1864.

    9. Noreen Morris, Gavin McLaughlin, Pierce V. Kavanagh, John D. Power, John
    O’Brien, Brian Talbot, Simon P. Elliott, Jason Wallach, K. Hoang, Hamilton
    Morris, Simon D. Brandt. Test purchase, synthesis and characterization of
    2-methoxydiphenidine (MXP) and differentiation from its meta- and
    para-substituted isomers. Drug Testing and Analysis. 2015, 8, 98-109. DOI:
    10.1002/dta.1800.

    10. Noreen Morris, Gavin McLaughlin, Pierce V. Kavanagh, John D. Power,
    Brendan Twamley, John O’Brien, Brian Talbot, Geraldine Dowling, Olivia
    Mahony, Simon D. Brandt, Julian Patrick, Roland P. Archer, John S. Partilla,
    Michael H. Baumann. Synthesis, characterization and monoamine transporter
    activity of the new psychoactive substance
    3’,4’-methylenedioxy-4-methylaminorex (MDMAR). Drug Testing and Analysis.
    2014, 7, 555-564. DOI: 10.1002/dta.1732.

    11. Noreen Morris, Jason Wallach,
    Pierce V. Kavanagh, Gavin McLaughlin, John D. Power, Simon P. Elliott, Marion
    S. Mercier, David Lodge, Hamilton Morris, Nicola M. Dempster, Simon D.
    Brandt. Preparation and characterization of the ‘research chemical’
    diphenidine, its pyrrolidine analogue, and their 2,2-diphenylethyl isomers.
    Drug Testing and Analysis. 2014, 7, 358-367. DOI: 10.1002/dta.1689

    .

    12. Noreen Morris, Fashli Razak, Vlasta Chyzna, Alan Murphy, James Kennedy.
    An investigation into the effects of pH and material concentrations on the
    morphology of Chitosan-Alginate microspheres prepared using an Ionic Gelation
    techniques”. International Journal
    of Advance Scientific Research and Management, Vol. 2 Issue 10, October 2017.

    13. Noreen Morris, Fashli Razak, James Kennedy, Alan Murphy. Development of
    Amoxicillin loaded microspheres for anti-Helicobacter pylori infection using
    Ionic Gelation Method. International Journal of Advance Scientific Research
    and Management, November 2017

    14. Noreen Morris, Maya Hotta, James Kennedy, Clem Higginbotham. Durum
    wheat seed germination response to hydrogel coatings and moisture under
    drought stress, American Journal of Agricultural and Biological Sciences, 11
    (2), 67-75 (2016).

    15. Noreen Morris, Maya Hotta, James Kennedy, Clem. Higginbotham.
    Development of seed coating agent with ι-carrageenan hydrogel for
    sustainable agriculture, Journal of the Institute of Chemistry of Ireland,
    July (3), 36-37 (2016).

    16. Noreen Morris, Maya Hotta, James Kennedy, Clem Higginbotham,
    “ι-Carrageenan hydrogel seed coating for drought mitigation &
    sustainable agriculture”, Environews (2017).

    17. Noreen Morris, Maya Hotta, James Kennedy, Clem Higginbotham. Synthesis
    and characterisation of novel ι-carrageenan hydrogel blends for agricultural
    seed coating application, Applied Mechanics and Materials, 679, 81-91
    (2014).

  • Teaching Experience

    Lecturing

    Experience: I lecture on undergraduate courses in the following
    modules:

    • Organic Chemistry;

    • Synthetic Organic Chemistry;

    • Pharmaceutical Materials;

    • Pharmaceutical Spectroscopy;

    • Pharmaceutical Synthesis;

    • Analytical techniques;

    • Contemporary issues in pharmaceutical science;

    • Medical devices and advanced therapies.

  • Interests & Professional Development
    "Scifest Co-ordinator: AIT Scifest co-ordinator providing an opportunity for second level students in the midlands to showcase their skills in Science Technology Engineering and Maths and at the same time to develop their critical thinking and problem solv
  • Membership of Academic/Professional Bodies

    MICI, MRSC. CChem